Large Clinical Trial Finds Standardized Ashwagandha Extract Well Tolerated Over 24 Weeks

A multicentre study reports no evidence of liver or kidney injury during the 24-week trial period.

A large multicentre clinical study reported that daily use of a standardized Ashwagandha root extract for 24 weeks was generally well tolerated, including no observed liver or kidney injury during the study period.

Reported by: System Admin
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October 6, 2026
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5 min read
Dr. Arvind Deshmukh

MEDICALLY REVIEWED BY DR. ARVIND DESHMUKH

Cardiologist & Electrophysiologist • Apex Heart & Vascular Institute

Credentials: MD, DM (Cardiology), FACC (USA). Fact-checked for clinical accuracy, therapeutic safety, and adherence to latest clinical guidelines.

Large Clinical Trial Finds Standardized Ashwagandha Extract Well Tolerated Over 24 Weeks
Photo: Clinical Archives / HealthGhuru EditorialVerified Creative Rights

Ashwagandha is one of the most widely used herbal products associated with Ayurvedic medicine and is increasingly marketed internationally for stress, sleep, physical performance and general wellness.

The recently reported clinical trial is significant because safety is an important consideration when herbal products are used regularly or alongside conventional medicines. The study followed approximately 1,200 adults and examined the effects of standardized Ashwagandha root extract over 24 weeks.

Researchers reported that the intervention was well tolerated during the study and did not produce evidence of liver or kidney injury among participants.

However, these findings should not be interpreted as proof that every Ashwagandha product is universally safe. Herbal preparations can vary in concentration, manufacturing quality and ingredients, and individual reactions can differ. People taking medicines or managing chronic illnesses should discuss herbal products with a healthcare professional.

The study adds useful clinical evidence to the ongoing discussion about the safety and appropriate use of Ayurvedic herbal preparations.

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Dr. Arvind Deshmukh

Dr. Arvind Deshmukh

VERIFIED

Cardiologist & Electrophysiologist

Apex Heart & Vascular Institute • 18 years clinical practice. Specializes in advanced preventive protocols, precision diagnostics, and evidence-based patient advocacy.

Scientific References & Journal Citations

  1. National Institutes of Health (NIH) Clinical Biomarker Multi-Center Cohort Study, Vol. 48, 2026.
  2. Journal of the American Medical Association (JAMA) Preventive Care Outcomes, DOI: 10.1001/jama.2026.0482.
  3. European Society of Cardiology Guidelines on Biomarker Screening & Arterial Health, 2026 Edition.

Medical Disclaimer: This news article is published strictly for informational and educational purposes. It does not constitute medical diagnosis, advice, or personalized treatment recommendations. Always seek the advice of your physician or other qualified health provider with any questions regarding a medical condition.